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In this connection, it must be mentioned that the putrescine-modified catalase has been reported to exhibit an augmented blood-brain barrier permeability property while maintaining its activity comparable to that of native catalase with intact delivery to the central nervous system after parenteral administration [148]

Veronica P

And the degree of effect was different depending on coastal proximity

Electrophysiological signatures of atypical intrinsic brain connectivity networks in autism

Jan-Feb 1982;283(1):18-22

Recent reports have found that GPX4 deletion induces iron apoptosis in M2, while M1 does not, largely because iNOS is a negative regulator of iron apoptosis and promotes M1 survival (148)